Despite the current focus on determining the precise genetic mutations responsible for malignant hyperthermia, there is still a lot that can be learned by conventional epidemiologic analysis. Dr. Sheila Riazi, Malignant Hyperthermia Investigation Unit, Toronto General Hospital, University Health Network, Toronto, Ontario, Canada, and colleagues describe nationwide epidemiology on malignant hyperthermia in Canada over a […]
A study of learning disability and academic achievement in children following anesthesia exposure in the first year of life.
When infants are exposed to anesthesia, does it affect learning abilities later in life? In neonatal animals, exposure to an anesthetic is unambiguously associated with neuroapoptosis (cell death) in the brain. Human studies have not been as unambiguous. Dr. Choon Bong, Department of Paediatric Anaesthesia, KK Women’s and Children’s Hospital, Yong Loo Lin School of […]
There has not been a recent review of perioperative care of patients with sickle cell disease. Dr. Paul G. Firth, Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA and colleagues used the Nationwide Inpatient Sample (NIS) database, maintained by the Agency for Healthcare Research and Quality to […]
Dexmedetomidine is now commonly used for sedation of patients undergoing diagnostic and therapeutic procedures. Given that the procedures include patients undergoing cardiac catheterization, it is important to know how dexmedetomidine affects pulmonary hemodynamics. To that end, Dr. Robert H. Friesen, Department of Anesthesiology, Children’s Hospital Colorado, University of Colorado, Aurora, CO and coauthors documented pulmonary […]
How far should an endotracheal tube be inserted into the trachea of a child? As with adults, the cuff of the tube should be inserted just beyond the vocal cords. If the tube is inserted too far, the tip of the tube may be inserted beyond the carina and only one lung will be ventilated. […]
Children undergoing anesthesia are known to have a greater likelihood of developing intraoperative hypoxemia in part due to reduced functional residual capacity and higher metabolic requirements compared to adults. How often do children become hypoxemic during anesthesia? Jurgen C. de Graaff, Department of Pediatric Anesthesia, Wilhelmina Children’s Hospital, Division of Anesthesiology, Intensive Care and Emergency […]