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Does surfactant reduce the severity of lung injury after hydrochloric acid instillation?

February 13, 2015 By J. Lance Lichtor in Critical Care, Trauma, and Resuscitation

Even with the resources available in the most modern intensive care units, the mortality in patients with respiratory distress syndrome remains high. Therapy is supportive, and there is no pharmacological therapy that demonstrably improves outcome. Dr. Giacomo Bellani, Department of Health Science, University of Milano-Bicocca, Monza, Italy, and Department of Emergency, San Gerardo Hospital, Monza, […]

Is the requirement of isoflurane dependent on cellular energy levels?

February 12, 2015 By J. Lance Lichtor in Anesthetic Pharmacology

The mechanism by which volatile anesthetics cause immobility to noxious stimulation remains a mystery. Can changes in energy levels affect the sensitivity to anesthetics? Dr. Zhongcong Xie, Geriatric Anesthesia Research Unit, Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital and Harvard Medical School, Charlestown, Massachusetts, and colleagues sought to determine whether 2-deoxy-d-glucose […]

Airway exchange catheters can create lung damage when they extend beyond the carina

February 11, 2015 By J. Lance Lichtor in Technology, Computing, and Simulation

Airway exchange catheters are semi-rigid. As such, they have the potential to damage the respiratory tract if mishandled when used for endotracheal tube exchange. Dr. Robert Axe, Department of Anaesthesia, Royql United hospital, Bath, England, and colleagues used pig trachea and lung specimens less than 48 h postmortem. These tracheas were intubated using 83 cm […]

Crystalloids versus colloids

February 5, 2015 By J. Lance Lichtor in Critical Care, Trauma, and Resuscitation

Crystalloids versus colloids: the argument never ceases. Adequate fluid administration plays a major role in the management of hospitalized patients. However, the choice of intravenous fluids and the place of colloids remain controversial. Some experts have recently challenged the physiological concept that less intravenous colloid need to be administered than crystalloids to achieve the same […]

Cardiopulmonary bypass use and bleeding: a study in neonates

February 3, 2015 By J. Lance Lichtor in Pediatric Anesthesiology

Adult patients who require transfusion following cardiopulmonary bypass (CPB) are at increased risk of adverse outcomes including death. Such studies have been done in children as well, with similar results, but none have previously been limited to neonates. Neonates may be more likely to bleed after cardiopulmonary bypass: the fixed bypass priming volumes are proportionally […]

Economic aspects of perioperative respiratory events: a study in children

January 30, 2015 By Richard Dutton in Pediatric Anesthesiology

Your patient’s oxygen saturation was < 95% for more than 10 seconds or perhaps your patient had laryngospasm during induction of anesthesia. Does it cost more to care for that patient? Dr. Maliwan Oofuvong, Department of Anesthesiology, Faculty of Medicine, Prince of Songkla University, Hat Yai, Songkhla, Thailand, and colleagues describe a prospective matched cohort study of […]