The January 2019 issue of Anesthesia & Analgesia has been published. Patient blood management is the timely application of evidence-based medical and surgical concepts designed to maintain hemoglobin concentration, optimize hemostasis, and minimize blood loss to improve patient outcomes. In their article, Zaleski and colleagues provide suggestions for successful, safe and bloodless treatment for patients including intraoperative and postoperative techniques to reduce blood loss and also introduce current innovative substitutes for transfusion. This article is discussed in an infographic and is featured on the cover of this issue.  In their review article, Zaleski and colleagues discuss the direct thrombin inhibitor, bivalirudin, which has found increasing use as a heparin alternative in the pediatric population most commonly for the treatment of thrombosis, secondary to heparin induced thrombocytopenia (HIT).  Due to the relative rarity of HIT as well as the lack of FDA-approved indications in this age group, much of what is known regarding pharmacokinetics and pharmacodynamics of bivalirudin in children has been extrapolated from adult data. The authors present recommendations regarding the use of bivalirudin for procedural anticoagulation in the pediatric population based upon the published literature. This article is discussed in an infographic in this issue.  All this and more can be found in the January 2019 issue of Anesthesia & Analgesia. We hope you enjoy reading the Journal. Questions or comments may be sent to us at